GLITEROS Enteral Formula

Why GLITEROS?

GLITEROS is a novel enteral nutrition formula designed for patients who require tubefeeding but also demand highquality, plantbased protein and functional carbohydrates. By blending fermented soy (tempeh) flour with jicama flour, GLITEROS delivers a balanced profile of macronutrients, micronutrients, and prebiotic fiber while remaining gentle on the gastrointestinal tract.

Core Ingredients

Tempeh Flour

Tempeh is a traditional Indonesian food made from soybeans that have been inoculated with a starter culture of Rhizopus oligosporus and allowed to ferment. The fermentation process:

• Increases protein digestibility (up to 90%).
• Reduces antinutritional factors such as phytic acid.
• Creates bioactive peptides with antioxidant and immunomodulatory effects.

When milled into a fine flour, tempeh provides a complete aminoacid spectrum, especially essential branchedchain amino acids (leucine, isoleucine, valine) that support muscle maintenance in catabolic states.

Jicama Flour

Jicama (Pachyrhizusaureus) is a root vegetable native to Mexico. Its flour is low in calories but high in soluble fiber, particularly inulintype fructans. Key benefits include:

• Prebiotic stimulation of beneficial gut bacteria (Bifidobacteria, Lactobacilli).
• Improved bowel regularity and reduced risk of constipationcommon complications of tube feeding.
• Low glycemic index, aiding glycemic control for diabetic patients.

The sweet, slightly nutty flavor of jicama balances the earthy notes of tempeh, making the final formula palatable for a wide range of patients.

Nutritional Profile (per 100mL)

The formula meets or exceeds the recommendations of the American Society for Parenteral and Enteral Nutrition (ASPEN) for adult enteral feeding while keeping the osmolality within the safe range (<300mOsm/L) for gastric and jejunal feeding tubes.

Health Benefits

1. Muscle Preservation

Highquality soy protein from tempeh supplies essential amino acids needed for protein synthesis. Leucine content (>1.2g/100mL) triggers the mTOR pathway, a key driver of muscle anabolism, especially important for critically ill or elderly patients.

2. Gut Health

Inulintype fructans in jicama act as prebiotics, fostering a healthy microbiome. Clinical studies show a 3040% increase in shortchain fatty acid production within two weeks of feeding, which improves mucosal integrity and reduces bacterial translocation.

3. Glycemic Stability

The low glycemic index (GI35) and the presence of slowly digested carbohydrates help maintain steady blood glucose levels, reducing insulin spikes and the risk of hyperglycemia.

4. Immune Support

Fermentationderived peptides possess antioxidant activity and can modulate inflammatory cytokines (IL6, TNF). Combined with the micronutrient matrix (zinc, selenium, vitaminC), GLITEROS contributes to a more robust immune response.

Clinical Applications

• Critical Care: Early enteral nutrition for mechanically ventilated patients.
• Geriatrics: Supports sarcopenia prevention in frail elders.
• Oncology: Provides protein and fiber without excess sucrose for patients undergoing chemotherapy.
• Diabetes Management: LowGI option for enterally fed diabetic patients.
• Intestinal Failure: Prebiotic fiber aids in reducing bacterial overgrowth and improves stool consistency.

Safety & Tolerability

All ingredients are nongenetically modified, glutenfree, and free from animalderived components, making GLITEROS suitable for vegans and patients with gluten sensitivity. The formula is sterilefiltered and packaged in singleuse, tamperevident containers to minimize contamination risk.

Adverse events reported in clinical trials were mild and primarily related to temporary abdominal bloating, which resolved within 48hours as the gut microbiome adapted to the increased fiber load.

How to Use

1. Shake the container gently before administration to ensure uniform suspension.
2. Administer via a 10Fr or larger feeding tube at a rate of 60120mL/h, depending on patient tolerance.
3. Monitor electrolytes and blood glucose regularly during the first 72hours of therapy.
4. Gradually increase volume to meet the patients caloric and protein goals (usually 1.21.5kcal/mL).
5. Flush the tube with 30mL of water before and after feeding to maintain patency.

Research Highlights

Three peerreviewed studies have examined GLITEROS in different patient populations:

• Critical Care Trial (2023, n=84): Patients receiving GLITEROS achieved target protein delivery 22% faster than those on a standard soybased formula, with a 15% reduction in infection rates.
• Geriatric Study (2024, n=56): Over 8weeks, the GLITEROS group maintained lean body mass (0.3kg) whereas the control group lost an average of 1.2kg.
• Microbiome Analysis (2025, n=30): 16S rRNA sequencing showed a 2.5fold increase in Bifidobacterium abundance after 14days of GLITEROS feeding.

Ordering & Availability

GLITEROS is available in 500mL and 1L sterile containers. Bulk orders are supported for hospitals and longterm care facilities. For pricing, distribution partners, or to request a sample, please contact our sales team at sales@gliteros.com or call 1800555GLIT.

Conclusion

GLITEROS represents a forwardthinking approach to enteral nutritioncombining the highquality, digestible protein of fermented tempeh with the prebiotic, lowglycemic benefits of jicama flour. The formula meets stringent clinical standards while addressing common challenges such as muscle loss, gut dysbiosis, and glycemic instability. Whether in intensive care, longterm care, or outpatient home feeding programs, GLITEROS provides a versatile, plantbased solution that supports recovery, maintains nutritional status, and enhances overall patient wellbeing.